[The Treatment of a Complex Regional Pain Syndrome]

Zh Nevrol Psikhiatr Im S S Korsakova. 1997;97(11):33-5.
[Article in Russian]


35 patients with complex regional pain syndrome (CRPS) were treated by hyperbaric oxygenation (HBO) and caffetin preparation. A significant decrease of pain was observed in all the patients after the treatment course. Intensity of pain was diminished according to visual analogous scale. Meanwhile considerable regression of autonomic disorders and weakening of anxious and depressive manifestations was noted too. The tendency to normalization of evoked skin potentials was also found. Some elevation of the threshold of nociceptive reflex was conditioned by displacement toward general increase of antinociception after the treatment. Effect of HBO therapy persisted during 6 months in 87% of the patients. Efficiency of caffetin was restricted by the time of its administration. The conclusion was made about possibility of successful treatment of CRPS patients by both methods.

Publication types

  • Comparative Study
  • English Abstract

MeSH terms

  • Acetaminophen / administration & dosage
  • Acute Disease
  • Anti-Inflammatory Agents, Non-Steroidal / administration & dosage
  • Antipyrine / administration & dosage
  • Antipyrine / analogs & derivatives
  • Caffeine / administration & dosage
  • Cerebrovascular Disorders / complications
  • Codeine / administration & dosage
  • Combined Modality Therapy
  • Drug Combinations
  • Evaluation Studies as Topic
  • Hand Injuries / complications
  • Humans
  • Hyperbaric Oxygenation
  • Leg Injuries / complications
  • Nerve Compression Syndromes / complications
  • Pain Measurement
  • Reflex Sympathetic Dystrophy / etiology
  • Reflex Sympathetic Dystrophy / psychology
  • Reflex Sympathetic Dystrophy / therapy*
  • Soft Tissue Injuries / complications


  • Anti-Inflammatory Agents, Non-Steroidal
  • Drug Combinations
  • caffeine, codeine, acetaminophen, propyphenazone drug combination
  • Acetaminophen
  • Caffeine
  • Codeine
  • Antipyrine