Tau protein concentrations in cerebrospinal fluid of non-demented Parkinson's disease patients

Neurosci Lett. 1997 Dec 5;238(3):139-41. doi: 10.1016/s0304-3940(97)00858-6.


We measured total tau protein concentrations in the cerebrospinal fluid (CSF) of 26 non-demented Parkinson's disease (PD) patients and 25 matched controls. When compared with controls, PD patients had similar CSF tau protein concentrations. These values were not correlated with age, age at onset of PD, duration of PD, scores of the Unified PD Rating Scale (UPDRS), and the Hoehn and Yahr staging, and were not influenced significantly by antiparkinsonian drugs. Our results suggest that CSF tau protein levels are apparently unrelated to the risk of PD.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Dementia / cerebrospinal fluid*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Parkinson Disease / cerebrospinal fluid*
  • tau Proteins / cerebrospinal fluid*


  • tau Proteins