Sleep deprivation can attenuate light-induced phase shifts of circadian rhythms in hamsters

Neurosci Lett. 1997 Nov 28;238(1-2):5-8. doi: 10.1016/s0304-3940(97)00815-x.


To determine whether sleep deprivation (SD) affects the response of circadian rhythms to light, hamsters were forced to walk on a slowly rotating treadmill for 6 or 24 h, ending early in the night, with or without a light pulse during the last 30 min. SD alone did not produce a significant phase shift. Light pulses (300 and 50 lx) alone induced significant delay shifts (55 and 35 min, respectively). Twenty-four hours SD significantly attenuated the delay to brighter light and 6 h SD significantly attenuated the delay to moderate light. Sleep loss or attendant low-intensity continuous activity appear to modulate the response of the hamster circadian system to light.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Behavior, Animal / physiology*
  • Circadian Rhythm / physiology*
  • Cricetinae / physiology*
  • Male
  • Motor Activity
  • Photoperiod*
  • Sleep Deprivation / physiology*