Imaging neuronal networks in behaving animals

Curr Opin Neurobiol. 1997 Dec;7(6):832-8. doi: 10.1016/s0959-4388(97)80143-2.


Neuronal activity has recently been imaged with single-cell resolution in behaving vertebrates. This was accomplished by using fluorescent calcium indicators in conjunction with confocal or two-photon microscopy. These optical techniques, along with other new approaches for imaging synaptic activity, second messengers, and neurotransmitters and their receptors offer great promise for the study of neuronal networks at high resolution in vivo.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Behavior, Animal / physiology*
  • Mammals / physiology
  • Nerve Net / anatomy & histology*
  • Nerve Net / cytology
  • Nerve Net / physiology*
  • Neurons / physiology
  • Zebrafish