A kinder, gentler genetic analysis of behavior: dissection gives way to modulation

Curr Opin Neurobiol. 1997 Dec;7(6):805-11. doi: 10.1016/s0959-4388(97)80139-0.


Many of the mutations and genetic variants that affect behavior in Drosophila have proved to be mild lesions of genes that are capable of more severe phenotypes. Examples of such variants affecting ion channels, transcription factors and protein kinases in studies of courtship and learning have anticipated recent findings on the naturally occurring variants in circadian rhythms and foraging.

Publication types

  • Review

MeSH terms

  • Animals
  • Behavior / physiology*
  • Drosophila
  • Genetics, Behavioral*
  • Humans
  • Mutation / physiology