Multifocal motor neuropathy without overt conduction block

Muscle Nerve. 1998 Feb;21(2):243-5. doi: 10.1002/(sici)1097-4598(199802)21:2<243::aid-mus14>;2-2.


One of the defining electrophysiological characteristics of multifocal motor neuropathy (MMN) is focal motor nerve conduction block. We have noted occasional patients with typical clinical features of MMN in whom there is no demonstrable conduction block. Upon review of 5 such cases, we conclude that otherwise typical MMN may present without overt conduction block. This subset of patients does not otherwise differ from patients with MMN in whom this hallmark electrodiagnostic feature is present.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Aged
  • Demyelinating Diseases / diagnosis*
  • Demyelinating Diseases / pathology
  • Demyelinating Diseases / physiopathology*
  • Diagnosis, Differential
  • Female
  • Humans
  • Male
  • Middle Aged
  • Motor Neuron Disease / diagnosis*
  • Motor Neuron Disease / pathology
  • Motor Neuron Disease / physiopathology
  • Neural Conduction*