Cone b-wave implicit time as an early predictor of rubeosis in central retinal vein occlusion

Am J Ophthalmol. 1998 Feb;125(2):247-9. doi: 10.1016/s0002-9394(99)80099-3.

Abstract

Purpose: To investigate the predictive value of the cone b-wave implicit time in the 30-Hz flicker electroretinogram for rubeosis in the acute phase of central retinal vein occlusion.

Methods: In a prospective study, 25 patients (25 eyes) with a central retinal vein occlusion of less than 14 days' duration were examined with electroretinography and followed up for a minimum of 18 months.

Results: The cone b-wave implicit time in the eyes that developed rubeosis (n = 11) was more than 37.1 milliseconds and in the eyes that did not develop rubeosis (n = 14), less than 37 milliseconds (P < .00001).

Conclusion: The cone b-wave implicit time in the 30-Hz flicker electroretinogram is a good predictor of rubeosis at an early stage in eyes with central retinal vein occlusion.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acute Disease
  • Dark Adaptation
  • Electroretinography
  • Humans
  • Middle Aged
  • Predictive Value of Tests
  • Prospective Studies
  • Retinal Cone Photoreceptor Cells / physiology*
  • Retinal Neovascularization / diagnosis*
  • Retinal Neovascularization / etiology
  • Retinal Neovascularization / physiopathology
  • Retinal Vein Occlusion / complications*