Vertical transmission of hepatitis C virus infection: usefulness of viremia detection in HIV-seronegative hepatitis C virus-seropositive mothers

J Pediatr. 1998 Jan;132(1):167-9. doi: 10.1016/s0022-3476(98)70507-4.


Seventy mother-newborn pairs were studied for hepatitis C viremia to evaluate the risk of vertical transmission of hepatitis C virus from human immunodeficiency virus-negative mothers. Forty-five mothers were hepatitis C virus-RNA positive: 4 to 45 children were positive at birth and during follow-up. The level of viremia plays an important role in vertical transmission.

MeSH terms

  • Female
  • HIV Seronegativity
  • Hepacivirus / isolation & purification*
  • Hepatitis C / congenital*
  • Hepatitis C / diagnosis
  • Hepatitis C / transmission*
  • Humans
  • Infant, Newborn
  • Infectious Disease Transmission, Vertical*
  • Pregnancy
  • Pregnancy Complications, Infectious / virology*
  • RNA, Viral / blood
  • Viremia / diagnosis


  • RNA, Viral