[Concept, classification and pathophysiology of status epilepticus]

Neurologia. 1997 Dec:12 Suppl 6:2-9.
[Article in Spanish]

Abstract

Status epilepticus (prolonged or repetitive seizures without a period of recovery between them) is a life-threatening medical emergency for which appropriate diagnosis and treatment are imperative. It is usually classified with a practical aim as convulsive and non-convulsive, generalized and partial. In convulsive status there is a critical period of 30 min before irreversible metabolic alterations appear. The factors that influence the beginning and endpoint of a status epilepticus are unknown but a role has been proposed for both glutamate mediates excitation and lack of GABA mediated inhibition.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Brain / physiopathology*
  • Humans
  • Status Epilepticus / diagnosis*
  • Status Epilepticus / metabolism
  • Status Epilepticus / physiopathology*
  • Time Factors
  • gamma-Aminobutyric Acid / metabolism

Substances

  • gamma-Aminobutyric Acid