Abstract
Fungal cells were observed infiltrating the submucosal margins of an acutely perforated gastric ulceration in an apparently immunocompetent 3-year-old girl. Perforation had occurred 24 h after hospital admission because of pain and vomiting. Colonies of Candida tropicalis were grown from peritoneal fluid and blood cultures. After surgical repair and a 30-day treatment with amphotericin B at a daily dose of 1 mg kg-1 body weight, the child was discharged in good health. No further infections have occurred in the 3 years since treatment.
MeSH terms
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Amphotericin B / therapeutic use
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Antifungal Agents / therapeutic use
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Candidiasis / complications*
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Candidiasis / therapy
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Child, Preschool
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Emergency Service, Hospital
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Female
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Humans
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Immunocompetence
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Male
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Pain
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Rupture, Spontaneous / complications
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Rupture, Spontaneous / microbiology
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Rupture, Spontaneous / therapy
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Stomach Rupture / complications*
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Stomach Rupture / microbiology
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Stomach Rupture / therapy
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Stomach Ulcer / complications*
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Stomach Ulcer / microbiology
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Stomach Ulcer / therapy
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Vomiting
Substances
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Antifungal Agents
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Amphotericin B