Cardiac angiosarcoma responding to multidisciplinary treatment

Int J Cardiol. 1997 Dec 19;62(3):273-5. doi: 10.1016/s0167-5273(97)00259-3.

Abstract

Early detection of cardiac angiosarcoma is usually difficult and the prognosis is very poor. We experienced a 32-year-old man with cardiac angiosarcoma who responded to multidisciplinary treatment with recombinant interleukin-2, postoperative chemotherapy (cyclophosphamide, vincristine, doxorubicin, Dacarbazine) and radiation. At 30 months after surgery, there was no evidence of recurrence or metastasis in spite of incomplete resection.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Cardiac Tamponade
  • Chemotherapy, Adjuvant
  • Coronary Angiography
  • Cyclophosphamide / administration & dosage
  • Cyclophosphamide / therapeutic use
  • Dacarbazine / administration & dosage
  • Dacarbazine / therapeutic use
  • Doxorubicin / administration & dosage
  • Doxorubicin / therapeutic use
  • Echocardiography
  • Heart Neoplasms / diagnosis
  • Heart Neoplasms / surgery
  • Heart Neoplasms / therapy*
  • Hemangiosarcoma / diagnosis
  • Hemangiosarcoma / surgery
  • Hemangiosarcoma / therapy*
  • Humans
  • Interleukin-2 / therapeutic use
  • Magnetic Resonance Imaging
  • Male
  • Radiotherapy, Adjuvant
  • Recombinant Proteins / therapeutic use
  • Vincristine / administration & dosage
  • Vincristine / therapeutic use

Substances

  • Interleukin-2
  • Recombinant Proteins
  • Vincristine
  • Dacarbazine
  • Doxorubicin
  • Cyclophosphamide

Supplementary concepts

  • CYVADIC protocol