Treatment of vaginal infections: candidiasis, bacterial vaginosis, and trichomoniasis

J Am Pharm Assoc (Wash). 1997 Sep-Oct;NS37(5):563-9. doi: 10.1016/s1086-5802(16)30241-8.

Abstract

Objective: To describe the signs and symptoms of and recommend treatments for Candida vulvovaginitis, bacterial vaginosis, and Trichomonas vaginitis.

Data sources: Current clinical literature.

Data synthesis: Patients with candidal vulvovaginitis often present with itching, burning, white discharge, vulvar or vaginal erythema, painful intercourse, and stinging on urination. It is treated with oral or topical antifungal agents. Bacterial vaginosis is characterized by a musty or fishy vaginal odor and a thin, white vaginal discharge. It is treated with oral or topical metronidazole or clindamycin. Patients with trichomoniasis usually complain of profuse, yellow-green discharge and vaginal or vulvar irritation. The standard treatment is a single 2 gram dose of oral metronidazole for both the patient and sexual partners.

Conclusion: Given the potential adverse effects of the drugs used to treat these conditions, pharmacists are in a unique position to recommend appropriate therapies and to refer patients to other health care providers as needed.

Publication types

  • Review

MeSH terms

  • Antifungal Agents / administration & dosage
  • Antifungal Agents / adverse effects
  • Antifungal Agents / therapeutic use*
  • Antitrichomonal Agents / administration & dosage
  • Antitrichomonal Agents / adverse effects
  • Antitrichomonal Agents / therapeutic use*
  • Candidiasis, Vulvovaginal / drug therapy*
  • Candidiasis, Vulvovaginal / epidemiology
  • Candidiasis, Vulvovaginal / microbiology
  • Drug Interactions
  • Female
  • Humans
  • Trichomonas Vaginitis / drug therapy*
  • Trichomonas Vaginitis / epidemiology
  • Vaginosis, Bacterial / drug therapy*
  • Vaginosis, Bacterial / epidemiology
  • Vaginosis, Bacterial / microbiology

Substances

  • Antifungal Agents
  • Antitrichomonal Agents