Interaction of reactive oxygen species with DNA. A review

Biochemistry (Mosc). 1997 Dec;62(12):1341-7.


Data on direct and indirect effects of reactive oxygen species on DNA are reviewed. The classification of the types of DNA oxidative damage and repair enzymes including glycosylases and endo- and exonucleases is presented. The regulatory function of reactive oxygen species and their role in carcinogenesis are discussed.

Publication types

  • Review

MeSH terms

  • DNA / chemistry*
  • DNA Damage
  • DNA Repair
  • Neoplasms / genetics
  • Neoplasms / pathology
  • Oxidative Stress
  • Reactive Oxygen Species*


  • Reactive Oxygen Species
  • DNA