[Treatment of acute attack of migraine with sumatriptan]

Rev Neurol. 1997 Nov;25(147):1672-5.
[Article in Spanish]

Abstract

Introduction and material: In the Hospital Clínico Quirúrgico Hermanos Almeijeiras a randomized double blind clinical trial was carried out involving 52 patients who presented with painful migraine crises with or without prodromes. A group of 27 patients were given 6 mg of sumatriptan subcutaneously. Another group of 25 patients were given 1 mg of dihydroergotamine intramuscularly. It was seen that both drugs relieved the migrainous pain. However, sumatriptan did so in a greater percentage of patients.

Results and conclusions: There was earlier, and also more complete, relief of pain in those patients receiving sumatriptan. With regard to side-effects of sumatriptan were pain at the back of the site of injection, sensation of pressure at the back of the neck, facial flushing and asthenia.

Publication types

  • Clinical Trial
  • English Abstract
  • Randomized Controlled Trial

MeSH terms

  • Acute Disease
  • Adolescent
  • Adult
  • Age Distribution
  • Double-Blind Method
  • Female
  • Humans
  • Male
  • Migraine Disorders / diagnosis
  • Migraine Disorders / drug therapy*
  • Serotonin Receptor Agonists / therapeutic use*
  • Severity of Illness Index
  • Sex Distribution
  • Sumatriptan / therapeutic use*
  • Time Factors

Substances

  • Serotonin Receptor Agonists
  • Sumatriptan