Intermediate filaments and their associated proteins: multiple dynamic personalities

Curr Opin Cell Biol. 1998 Feb;10(1):93-101. doi: 10.1016/s0955-0674(98)80091-4.


A fusion of mouse and human genetics has now proven that intermediate filaments form a flexible scaffold essential for structuring cytoplasm in a variety of cell contexts. In some cases, the formation of this scaffold is achieved through a newly identified family of intermediate-filament-associated proteins that form cross-bridges between intermediate filaments and other cytoskeletal elements, including actin and microtubules.

Publication types

  • Review

MeSH terms

  • Animals
  • Humans
  • Intermediate Filament Proteins / physiology*
  • Intermediate Filaments / physiology*
  • Mice


  • Intermediate Filament Proteins