Craniofacial resection for tumors of the nasal cavity and paranasal sinuses--a 17-year experience

Head Neck. 1998 Mar;20(2):97-105. doi: 10.1002/(sici)1097-0347(199803)20:2<97::aid-hed1>3.0.co;2-y.

Abstract

Background: The rarity of sinonasal tumors has precluded long-term follow-up of large series of craniofacial resections until now.

Methods: A series of 209 patients suffering from a wide range of histologies who had undergone craniofacial resection for sinonasal neoplasia with up to 17 years' follow-up were analyzed.

Results: An overall actuarial survival of 51% at 5 years and 41% at 10 years was found for the cohort as a whole. For malignant tumors, the 5-year actuarial survival was 44%, falling to 32% at 10 years. For benign pathology, the actuarial survival was 75% at both 5 and 10 years. Statistical analysis identified three factors which significantly affect outcome and survival: malignant histology, brain involvement, and orbital involvement. Few complications are associated with the surgery, with the mean post-operative stay being 16 days.

Conclusions: The improved survival and minimal morbidity and mortality associated with craniofacial resection make it the optimum approach to sinonasal tumors.

MeSH terms

  • Actuarial Analysis
  • Adenocarcinoma / pathology
  • Adenocarcinoma / surgery
  • Adolescent
  • Adult
  • Aged
  • Brain Neoplasms / pathology
  • Carcinoma, Squamous Cell / pathology
  • Chemotherapy, Adjuvant
  • Child
  • Cohort Studies
  • Disease-Free Survival
  • Esthesioneuroblastoma, Olfactory / pathology
  • Facial Bones / surgery*
  • Fascia Lata / transplantation
  • Female
  • Follow-Up Studies
  • Humans
  • Length of Stay
  • Logistic Models
  • Longitudinal Studies
  • Male
  • Middle Aged
  • Multivariate Analysis
  • Neoplasm Invasiveness
  • Nose Neoplasms / pathology
  • Nose Neoplasms / surgery*
  • Orbital Neoplasms / pathology
  • Osteotomy / adverse effects
  • Osteotomy / methods
  • Paranasal Sinus Neoplasms / pathology
  • Paranasal Sinus Neoplasms / surgery*
  • Radiotherapy, Adjuvant
  • Skin Transplantation / adverse effects
  • Skin Transplantation / methods
  • Skull / surgery*
  • Survival Analysis
  • Treatment Outcome