Transcranial magnetic stimulation selectively impairs interhemispheric transfer of visuo-motor information in humans

Exp Brain Res. 1998 Feb;118(3):435-8. doi: 10.1007/s002210050299.

Abstract

We investigated the cerebral cortical route by which visual information reaches motor cortex when visual signals are used for manual responses. Subjects responded unimanually to photic stimuli delivered to the hemifield ipsilateral or contralateral to the moving hand. On some trials, trans-cranial magnetic stimulation (TMS) was applied unilaterally over the occiput, with the aim of stimulating extrastriate visual areas and thereby modifying transmission of visual input. In association with the side of a visual stimulus and a motor response, TMS could change inter- or intra-hemispheric transmission needed to convey visual information to motor areas. Reaction time differences following TMS suggested that TMS exerted an inhibitory effect only when visuo-motor information had to be transferred interhemispherically. This result reinforces evidence for an extrastriate pathway of interhemispheric transfer of visuomotor information.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Acoustic Stimulation
  • Adult
  • Brain / physiology*
  • Brain / radiation effects
  • Female
  • Functional Laterality
  • Humans
  • Male
  • Middle Aged
  • Motor Activity
  • Psychomotor Performance / physiology*
  • Psychomotor Performance / radiation effects
  • Reaction Time
  • Reference Values
  • Transcranial Magnetic Stimulation*
  • Visual Pathways / physiology
  • Visual Perception