Glycemia and regulation of endothelial adhesion molecules

Horm Metab Res. 1997 Dec;29(12):636-8. doi: 10.1055/s-2007-979116.


Hyperglycemia is one of the most prominent factors associated with diabetic vascular disease, the development of which is initated by functional and morphological alterations of the endothelium. The review summarizes several issues of glycemia and advanced glycation end products induced changes concerning soluble as well as cell bound endothelial adhesion molecules, and further addresses the aspect of apoptosis in the light of diabetic vascular complications.

Publication types

  • Review

MeSH terms

  • Apoptosis
  • Cell Adhesion Molecules / metabolism*
  • Endothelium, Vascular / metabolism*
  • Endothelium, Vascular / pathology
  • Glycation End Products, Advanced / metabolism
  • Humans
  • Hyperglycemia / metabolism*
  • Hyperglycemia / pathology


  • Cell Adhesion Molecules
  • Glycation End Products, Advanced