Streptococcus pneumoniae bacteremia in a community hospital

Chest. 1998 Feb;113(2):387-90. doi: 10.1378/chest.113.2.387.

Abstract

We reviewed 71 consecutive patients with Streptococcus pneumoniae bacteremia. The patients were analyzed by age, sex, ethnic background, and clinical presentation. Laboratory data reviewed included a CBC count, electrolyte levels, liver function studies, chest radiograph, HIV status, a sputum culture and Gram's stain, and sensitivities for the S pneumoniae isolated. Modalities of therapy, response to treatment, and ultimate outcome were examined. Many of the patients with pneumococcal bacteremia did not have cough, fever, or chills. HIV positivity was a risk factor for pneumococcal infection although it was not associated with increased mortality. Mortality correlated with elderly status, leukopenia, and lack of fever. Many patients had symptoms suggestive of atypical pneumonia including myalgia and mental status change. Hyponatremia and hyperbilirubinemia were commonly noted.

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Aged
  • Bacteremia / drug therapy
  • Bacteremia / physiopathology*
  • Blood Cell Count
  • Cognition Disorders / physiopathology
  • Cough / physiopathology
  • Drug Resistance, Microbial
  • Electrolytes / blood
  • Ethnic Groups
  • Female
  • Fever / physiopathology
  • HIV Seropositivity / physiopathology
  • Hospitals, Community
  • Humans
  • Hyperbilirubinemia / physiopathology
  • Hyponatremia / physiopathology
  • Leukopenia / physiopathology
  • Liver / physiopathology
  • Male
  • Middle Aged
  • Pneumococcal Infections / blood
  • Pneumococcal Infections / diagnostic imaging
  • Pneumococcal Infections / drug therapy
  • Pneumococcal Infections / physiopathology*
  • Pneumonia, Pneumococcal / physiopathology
  • Radiography
  • Remission Induction
  • Retrospective Studies
  • Risk Factors
  • Sex Factors
  • Sputum / microbiology
  • Streptococcus pneumoniae / drug effects
  • Survival Rate
  • Treatment Outcome

Substances

  • Electrolytes