Telomeres and senescence: the history, the experiment, the future

Curr Biol. 1998 Feb 26;8(5):R178-81. doi: 10.1016/s0960-9822(98)70105-8.

Abstract

Telomere length has been proposed to signal entry into cellular senescence. Expression of the human telomerase subunit, hTERT, in primary cells now shows that these cells bypass senescence.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Aging / physiology*
  • Animals
  • Humans
  • Telomerase / metabolism
  • Telomere / physiology*

Substances

  • Telomerase