Type 2 diabetes: when insulin secretion fails to compensate for insulin resistance

Cell. 1998 Mar 6;92(5):593-6. doi: 10.1016/s0092-8674(00)81125-3.
No abstract available

Publication types

  • Review

MeSH terms

  • Animals
  • Diabetes Mellitus, Type 2 / genetics
  • Diabetes Mellitus, Type 2 / metabolism*
  • Humans
  • Insulin / metabolism*
  • Insulin Receptor Substrate Proteins
  • Insulin Resistance / physiology*
  • Insulin Secretion
  • Intracellular Signaling Peptides and Proteins
  • Mice
  • Phosphoproteins / genetics
  • Phosphoproteins / physiology
  • Receptor, Insulin / genetics
  • Receptor, Insulin / physiology
  • Signal Transduction / physiology

Substances

  • IRS2 protein, human
  • Insulin
  • Insulin Receptor Substrate Proteins
  • Intracellular Signaling Peptides and Proteins
  • Irs2 protein, mouse
  • Phosphoproteins
  • Receptor, Insulin