Resormycin, a novel herbicidal and antifungal antibiotic produced by a strain of Streptomyces platensis. I. Taxonomy, production, isolation and biological properties

J Antibiot (Tokyo). 1997 Dec;50(12):1020-5. doi: 10.7164/antibiotics.50.1020.

Abstract

Resormycin, a novel herbicidal and antifungal antibiotic, was isolated from the cultured broth of streptomycete strain. The strain was isolated from a soil collected at Yokohama-shi, Kanagawa Prefecture, Japan, and identified as Streptomyces platensis MJ953-SF5. Resormycin was purified by active charcol, Amberlite IRC-50, Amberlite CG-50 and Sephadex LH-20 column chromatographies. Resormycin markedly inhibited the growth of monocotyledonous and dicotyledonous weed. The antibiotic showed antimicrobial activity against phytopathogenic fungi.

MeSH terms

  • Antifungal Agents / biosynthesis
  • Antifungal Agents / isolation & purification*
  • Antifungal Agents / pharmacology
  • Bacteria / drug effects
  • Culture Media
  • Fungi / drug effects
  • Herbicides / isolation & purification*
  • Herbicides / pharmacology
  • Hydrogen-Ion Concentration
  • Lactuca / drug effects
  • Plants / drug effects
  • Propionates / chemistry*
  • Propionates / isolation & purification
  • Streptomyces / chemistry*
  • Streptomyces / classification

Substances

  • Antifungal Agents
  • Culture Media
  • Herbicides
  • Propionates
  • resormycin