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, 58 (2), 259-63

A Simple Estimate of Glomerular Filtration Rate in Children Derived From Body Length and Plasma Creatinine

  • PMID: 951142

A Simple Estimate of Glomerular Filtration Rate in Children Derived From Body Length and Plasma Creatinine

G J Schwartz et al. Pediatrics.

Abstract

Based on statistical analysis of data in 186 children, a formula was derived which allows accurate estimation of glomerular filtration rate (GFR) from plasma creatinine and body lenght (GFR(ml/min/1.73 sq m) = 0.55 length (cm)/Per (mg/dl). Its application to clearance data in a separate group of 223 children reveals excellent agreement with GFR estimated by the Ccr (r = .935) or Cin (r = .905). This formula should be useful for adjusting dosages of drugs excreted by the kidney and detecting significant changes in renal function.

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