Dendritic cells

Curr Opin Hematol. 1998 Jan;5(1):3-15. doi: 10.1097/00062752-199801000-00002.


Dendritic cells are potent stimulators of immune responses against foreign antigens. Recent advances in this area include the delineation of distinct developmental pathways for different dendritic cell subsets; the emerging concept that one dendritic cell subset has regulatory functions that may contribute to induction of tolerance to self antigens; increased understanding of the interaction of dendritic cells with microbial products and viruses, such as HIV; and the application of dendritic cells for immunotherapy in certain cancers and possibly for the induction of transplantation tolerance.

Publication types

  • Review

MeSH terms

  • Animals
  • Dendritic Cells / cytology*
  • Dendritic Cells / immunology*
  • Humans
  • Immunotherapy
  • Langerhans Cells / immunology
  • Lymphoma, B-Cell / therapy
  • Mice
  • Neoplasms / therapy