Divergent corticostriatal projections from a single cortical column in the somatosensory cortex of rats

Brain Res. 1998 Mar 2;785(2):341-6. doi: 10.1016/s0006-8993(97)01363-2.


We injected biotinylated dextran amine (BDA) into single vibrissal 'barrels' of primary somatosensory (SI) cortex and reconstructed the topography of labelled varicosities in the dorsolateral caudate-putamen. Plots of labelled varicosities revealed densely-packed clusters of corticostriatal arborizations along the dorsolateral edge of the caudate-putamen and sparsely-packed arborizations more medially. The medial and lateral clusters of labelled terminals were separated by regions of unlabelled neuropil and lead us to conclude that a single cortical column sends divergent projections to multiple regions of the caudate-putamen.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Afferent Pathways / anatomy & histology
  • Afferent Pathways / physiology
  • Animals
  • Axonal Transport
  • Biotin / analogs & derivatives
  • Brain Mapping*
  • Caudate Nucleus / anatomy & histology
  • Caudate Nucleus / physiology*
  • Dextrans
  • Fluorescent Dyes
  • Putamen / anatomy & histology
  • Putamen / physiology*
  • Rats
  • Rats, Sprague-Dawley
  • Somatosensory Cortex / anatomy & histology
  • Somatosensory Cortex / physiology*
  • Vibrissae / innervation*


  • Dextrans
  • Fluorescent Dyes
  • biotinylated dextran amine
  • Biotin