An ancient system of host defense

Curr Opin Immunol. 1998 Feb;10(1):12-5. doi: 10.1016/s0952-7915(98)80024-1.


Research over the past few years has begun to provide significant advances in our understanding of the interplay between the innate and adaptive immune systems. New findings in several model systems reveal remarkable parallels and conservation of ancient host defense pathways in organisms separated by over a billion years of evolution.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Biological Evolution*
  • Drosophila / immunology
  • Humans
  • Immunity, Innate / immunology*
  • Mammals / immunology
  • Plants / immunology