Plasminogen/plasminogen activator and growth factor activation

D B Rifkin; P E Gleizes; J Harpel; I Nunes; J Munger; R Mazzieri; I Noguera

doi:10.1002/9780470515457.ch7

Plasminogen/plasminogen activator and growth factor activation

Ciba Found Symp. 1997:212:105-15; discussion 116-8. doi: 10.1002/9780470515457.ch7.

Authors

D B Rifkin¹, P E Gleizes, J Harpel, I Nunes, J Munger, R Mazzieri, I Noguera

Affiliation

¹ Department of Cell Biology, New York University Medical Center, NY 10016, USA.

PMID: 9524766
DOI: 10.1002/9780470515457.ch7

Abstract

The plasminogen/plasminogen activator system is widely used in extracellular proteolysis. In this review the involvement of this system in tumour invasion, cell migration, growth factor presentation and inhibition of angiogenesis are discussed.

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.
Review

MeSH terms

Animals
Growth Substances / metabolism*
Humans
Hydrolysis
Neoplasm Invasiveness
Plasminogen / metabolism*
Plasminogen Activators / metabolism*
Proteins / metabolism*
Stimulation, Chemical
Transforming Growth Factor beta / biosynthesis

Substances

Growth Substances
Proteins
Transforming Growth Factor beta
Plasminogen
Plasminogen Activators