The genotypic distribution of relatives of homozygotes when consanguinity is present

Ann Hum Genet. 1976 May;39(4):493-6. doi: 10.1111/j.1469-1809.1976.tb00157.x.

Abstract

A correction is made to an expression given by Jacquard (1968, 1972a,b) for the genotypic distribution of a relative of a given homozygote when consanguinity is present. The correction will necessarily be small either if the allele present in the given homozygote has a frequency of near unity, or if the coefficient of inbreeding of the given homozygote is small.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Alleles
  • Consanguinity*
  • Female
  • Gene Frequency
  • Genotype*
  • Homozygote
  • Humans
  • Male
  • Models, Biological*
  • Pedigree