Erythema multiforme in children. Response to treatment with systemic corticosteroids

Br J Dermatol. 1976 Aug;95(2):181-6. doi: 10.1111/j.1365-2133.1976.tb00824.x.


It is generally accepted that the correct treatment for patients with severe erythema multiforme is systemic corticosteroids. This paper is a review of thirty-two paediatric patients with severe erythema multiforme (Stevens-Johnson syndrome) who were treated with either large doses of systemic corticosteroids or supportive care only. Those patients treated with steroids did not recover sooner than those treated in other fashions and the steroid treated group had a significant incidence of medical complications. This retrospective study proves nothing but it does suggest that treatment of patients with the Stevens-Johnson syndrome with systemic corticosteroids may be associated with significant side effects and prolonged recovery.

Publication types

  • Comparative Study

MeSH terms

  • Adolescent
  • Adrenal Cortex Hormones / administration & dosage*
  • Adrenal Cortex Hormones / adverse effects
  • Adrenal Cortex Hormones / therapeutic use
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Infant
  • Length of Stay
  • Male
  • Stevens-Johnson Syndrome / complications
  • Stevens-Johnson Syndrome / drug therapy*


  • Adrenal Cortex Hormones