Abstract
Myb transcription factors are crucial to the control of proliferation and differentiation in a number of cell types but their mechanism of action is unclear. Regulation of Myb proteins by phosphorylation and intermolecular cooperation has recently been demonstrated, together with a new role for the proteins, in the control of apoptosis.
MeSH terms
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Animals
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Cell Cycle Proteins*
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Cell Death
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Cell Differentiation
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Cell Survival
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DNA-Binding Proteins / genetics
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DNA-Binding Proteins / physiology*
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Humans
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Proto-Oncogene Proteins / genetics
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Proto-Oncogene Proteins / physiology*
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Proto-Oncogene Proteins c-myb
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Trans-Activators / genetics
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Trans-Activators / physiology*
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Transcription Factors / genetics
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Transcription Factors / physiology*
Substances
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Cell Cycle Proteins
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DNA-Binding Proteins
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MYBL1 protein, human
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MYBL2 protein, human
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Proto-Oncogene Proteins
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Proto-Oncogene Proteins c-myb
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Trans-Activators
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Transcription Factors