Lipoblastoma: a case with t(7;8)(q31;q13)

Cancer Genet Cytogenet. 1998 Apr 1;102(1):12-4. doi: 10.1016/s0165-4608(97)00272-0.


Lipoblastoma is a rare benign adipose tumor which, in all of the cases so far described, presents an involvement of chromosome 8 in the region 8q11-13. We hereby report the results of the second case of lipoblastoma studied by fluorescence in situ hybridization (FISH), in a 13-month-old boy. An abnormal karyotype 46,XY,t(7;8)(q31;q13) was found in 90% of the metaphases examined, in agreement with the previously reported observations. We suggest the region 8q11-13 may contain a relevant locus for lipoblastoma origin.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Chromosomes, Human, Pair 7*
  • Chromosomes, Human, Pair 8*
  • Humans
  • In Situ Hybridization, Fluorescence
  • Infant
  • Karyotyping
  • Lipoma / genetics*
  • Lipoma / pathology
  • Male
  • Translocation, Genetic*