[Collagen metabolism in the skin with different vitamin K regimens]

Biull Eksp Biol Med. 1976 Jun;81(6):665-6.
[Article in Russian]


Secondary vitamin K deficiency in rats caused by pelentan was accompanied by a decrease in the total collagen content and a rise in free oxyproline in the skin. Under these conditions the rate of collagen hydrolysis proved to increase. Vitamin K (vikasol) prevented development of the mentioned shifts in collagen metabolism.

Publication types

  • English Abstract

MeSH terms

  • Animals
  • Collagen / metabolism*
  • Ethyl Biscoumacetate
  • Hydroxyproline / metabolism
  • Rats
  • Skin / metabolism*
  • Vitamin K / physiology*
  • Vitamin K Deficiency / chemically induced
  • Vitamin K Deficiency / metabolism


  • Ethyl Biscoumacetate
  • Vitamin K
  • Collagen
  • Hydroxyproline