High-dose intravenous immunoglobulin in transient neonatal myasthenia gravis

Pediatr Neurol. 1998 Feb;18(2):181-3. doi: 10.1016/s0887-8994(97)00174-4.


A preterm newborn had transient neonatal myasthenia gravis and was mechanically ventilated for 9 days. In addition to the usual supportive care, she was treated with neostigmine and underwent two exchange transfusions. High-dose intravenous immunoglobulin therapy (2 gm/kg) was used for the first time in transient neonatal myasthenia gravis to the best of our knowledge. The clinical and laboratory responses are presented.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Autoantibodies / blood
  • Female
  • Humans
  • Immunoglobulins, Intravenous / therapeutic use*
  • Infant, Newborn
  • Myasthenia Gravis / immunology
  • Myasthenia Gravis / therapy*
  • Receptors, Cholinergic / immunology


  • Autoantibodies
  • Immunoglobulins, Intravenous
  • Receptors, Cholinergic