Cardiac troponin T in newborn infants with transient myocardial ischemia

Biol Neonate. 1998;73(3):161-5. doi: 10.1159/000013973.


Cardiac troponin T (TnT) is a regulatory contractile protein whose detection in the circulation has been shown to be a specific and sensitive marker for ischemic myocardial cell injury both in adult and pediatric populations. We measured serum cardiac TnT in 15 consecutive full-term neonates presenting with bradycardia and electrocardiographic features of transient myocardial ischemia. Their median TnT concentrations (0.5 microg/l, range 0.01-0.37) were statistically comparable to our laboratory reference values for healthy term newborns (median 0.17 microg/l, range 0.01-0.42) (p = NS), but significantly higher with respect to our reference limits for healthy adults (median 0.01 micog/l, range 0.01-0.1) (p < 0.05). Our data demonstrate high TnT levels in neonates during the first days of life with respect to adults and similar TnT concentrations in term infants with and without TMI.

MeSH terms

  • Bradycardia
  • Electrocardiography
  • Humans
  • Infant, Newborn
  • Myocardial Ischemia / blood*
  • Myocardial Ischemia / diagnosis
  • Reference Values
  • Troponin / blood*
  • Troponin T


  • Troponin
  • Troponin T