Rapidly progressive glomerulonephritis in a boy with hypocomplementaemic urticarial vasculitis

Eur J Pediatr. 1998 Mar;157(3):243-5. doi: 10.1007/s004310050804.

Abstract

The present paper reports the fourth case of hypocomplementaemic urticarial vasculitis in a child. We describe a boy who, after many years of arthritis, urticaria, eye inflammation and hypocomplementaemia, developed rapidly progressive glomerulonephritis which was completely reversed by immunosuppressive therapy.

Conclusion: Only three paediatric patients with hypocomplementaemic urticarial vasculitis have been described. Severe renal involvement was reversible with early appropriate treatment.

Publication types

  • Case Reports

MeSH terms

  • Adrenal Cortex Hormones / therapeutic use
  • Azathioprine / therapeutic use
  • Biopsy, Needle
  • Child, Preschool
  • Complement System Proteins / deficiency*
  • Disease Progression
  • Disease-Free Survival
  • Drug Therapy, Combination
  • Glomerulonephritis / drug therapy*
  • Glomerulonephritis / etiology*
  • Glomerulonephritis / pathology
  • Humans
  • Immunosuppressive Agents / therapeutic use
  • Male
  • Urticaria / complications*
  • Urticaria / immunology
  • Vasculitis, Leukocytoclastic, Cutaneous / complications*
  • Vasculitis, Leukocytoclastic, Cutaneous / immunology

Substances

  • Adrenal Cortex Hormones
  • Immunosuppressive Agents
  • Complement System Proteins
  • Azathioprine