Abstract
The present paper reports the fourth case of hypocomplementaemic urticarial vasculitis in a child. We describe a boy who, after many years of arthritis, urticaria, eye inflammation and hypocomplementaemia, developed rapidly progressive glomerulonephritis which was completely reversed by immunosuppressive therapy.
Conclusion:
Only three paediatric patients with hypocomplementaemic urticarial vasculitis have been described. Severe renal involvement was reversible with early appropriate treatment.
MeSH terms
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Adrenal Cortex Hormones / therapeutic use
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Azathioprine / therapeutic use
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Biopsy, Needle
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Child, Preschool
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Complement System Proteins / deficiency*
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Disease Progression
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Disease-Free Survival
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Drug Therapy, Combination
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Glomerulonephritis / drug therapy*
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Glomerulonephritis / etiology*
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Glomerulonephritis / pathology
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Humans
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Immunosuppressive Agents / therapeutic use
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Male
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Urticaria / complications*
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Urticaria / immunology
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Vasculitis, Leukocytoclastic, Cutaneous / complications*
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Vasculitis, Leukocytoclastic, Cutaneous / immunology
Substances
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Adrenal Cortex Hormones
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Immunosuppressive Agents
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Complement System Proteins
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Azathioprine