Severe cholestatic hepatitis following cloxacillin treatment

S Goland; S D Malnick; R Gratz; E Feldberg; D Geltner; Z M Sthoeger

doi:10.1136/pgmj.74.867.59

Severe cholestatic hepatitis following cloxacillin treatment

Postgrad Med J. 1998 Jan;74(867):59-60. doi: 10.1136/pgmj.74.867.59.

Authors

S Goland¹, S D Malnick, R Gratz, E Feldberg, D Geltner, Z M Sthoeger

Affiliation

¹ Department of Internal Medicine C, Kaplan Hospital, Rehovot, Israel.

Abstract

We describe a 77-year-old woman who developed fatigue, fever, a maculopapular rash and severe cholestatic hepatitis two weeks after receiving cloxacillin and ofloxacin.

Publication types

Case Reports

MeSH terms

Aged
Cholestasis / chemically induced*
Cholestasis / drug therapy
Cloxacillin / adverse effects*
Female
Glucocorticoids / therapeutic use
Humans
Penicillins / adverse effects*
Prednisone / therapeutic use
Treatment Outcome

Substances

Glucocorticoids
Penicillins
Cloxacillin
Prednisone