Trans-acting factor(s) confer glucose-responsive transcriptional regulation in the insulin gene

Adv Exp Med Biol. 1997:426:97-100. doi: 10.1007/978-1-4899-1819-2_13.

Authors

S Goodison¹, S J Ashcroft

Affiliation

¹ University of Oxford, Nuffield Dept. of Clinical Biochemistry, John Radcliffe Hospital, Headington, United Kingdom.

PMID: 9544261
DOI: 10.1007/978-1-4899-1819-2_13

No abstract available

MeSH terms

Animals
Cell Line
Cell Nucleus / metabolism
Gene Expression Regulation / drug effects*
Genes, Reporter
Glucose / pharmacology*
Insulin / biosynthesis*
Insulin / genetics
Islets of Langerhans / metabolism*
Promoter Regions, Genetic
Recombinant Fusion Proteins / biosynthesis
Trans-Activators / metabolism*
Transcription, Genetic / drug effects*
Transfection

Substances

Insulin
Recombinant Fusion Proteins
Trans-Activators
Glucose