Regional cerebral blood flow during seizures in neonates

J Pediatr. 1998 Mar;132(3 Pt 1):431-5. doi: 10.1016/s0022-3476(98)70015-0.


With the use of 99mTc-D, L,-hexamethylpropylenamine oxime and single photon emission computed tomography, regional cerebral blood flow was measured ictally in 12 mature infants with recurrent seizures and compared with a reference group of nine interictal studies. The study indicates that both clinical and electrical seizures in neonates are associated with a focal cerebral hyperperfusion of the same amount as seen in adults.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Brain / blood supply
  • Brain / diagnostic imaging
  • Cerebrovascular Circulation*
  • Electroencephalography
  • Humans
  • Infant
  • Infant, Newborn
  • Seizures / etiology
  • Seizures / physiopathology*
  • Tomography, Emission-Computed, Single-Photon