Population genetics: surviving under mutation pressure

Curr Biol. 1998 Mar 26;8(7):R235-7. doi: 10.1016/s0960-9822(98)70148-4.


Concern has been voiced about the survival of endangered species, and even the long-term prospects for humans, in the face of accumulating deleterious mutations. Two experiments have investigated the mutation accumulation process in laboratory Drosophila populations, with apparently conflicting results.

Publication types

  • Review

MeSH terms

  • Animals
  • Drosophila / genetics
  • Female
  • Genetics, Population*
  • Humans
  • Male
  • Models, Genetic
  • Mutation*
  • Selection, Genetic