Isolation of a new member of DnaJ-like heat shock protein 40 (Hsp40) from human liver

Biochim Biophys Acta. 1998 Mar 3;1383(1):4-8. doi: 10.1016/s0167-4838(97)00207-0.


A new member of Hsp40, HLJ1, consisting of 337 amino acids, was cloned from a human liver cDNA library. The deduced amino acid sequence of HLJ1 has an 84% homology (69% identity) with that of HDJ-1 isolated from human placenta. Northern analysis showed that expression of the HLJ1 gene is heat-inducible and its transcription shows some degree of preference in heart, skeletal muscle, and pancreas.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Base Sequence
  • Cloning, Molecular
  • Gene Library
  • HSP40 Heat-Shock Proteins
  • Heat-Shock Proteins / isolation & purification*
  • Humans
  • Liver / chemistry*
  • Molecular Sequence Data
  • Placenta / chemistry
  • Sequence Homology, Amino Acid


  • DNAJB1 protein, human
  • DNAJB4 protein, human
  • HSP40 Heat-Shock Proteins
  • Heat-Shock Proteins

Associated data

  • GENBANK/U40992