The multienzyme PDE4 cyclic adenosine monophosphate-specific phosphodiesterase family: intracellular targeting, regulation, and selective inhibition by compounds exerting anti-inflammatory and antidepressant actions

Adv Pharmacol. 1998;44:225-342. doi: 10.1016/s1054-3589(08)60128-3.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • 3',5'-Cyclic-AMP Phosphodiesterases / genetics
  • 3',5'-Cyclic-AMP Phosphodiesterases / physiology*
  • Amino Acid Sequence
  • Animals
  • Anti-Inflammatory Agents, Non-Steroidal / therapeutic use*
  • Antidepressive Agents / therapeutic use*
  • Cyclic Nucleotide Phosphodiesterases, Type 4
  • Depressive Disorder / drug therapy
  • Depressive Disorder / enzymology*
  • Enzyme Inhibitors / therapeutic use*
  • Humans
  • Inflammation / drug therapy
  • Inflammation / enzymology*
  • Molecular Sequence Data
  • Phosphodiesterase Inhibitors / therapeutic use*
  • Sequence Alignment

Substances

  • Anti-Inflammatory Agents, Non-Steroidal
  • Antidepressive Agents
  • Enzyme Inhibitors
  • Phosphodiesterase Inhibitors
  • 3',5'-Cyclic-AMP Phosphodiesterases
  • Cyclic Nucleotide Phosphodiesterases, Type 4