Hepatitis C associated with Guillain-Barré syndrome

Liver. 1998 Feb;18(1):49-51. doi: 10.1111/j.1600-0676.1998.tb00126.x.


Hepatitis C is frequently associated with immune-mediated diseases, such as cryoglobulinemia. Guillain-Barré syndrome is an acute demyelinating neuropathy of probable immune pathogenesis. We describe two patients with Guillain-Barré syndrome, and associated chronic hepatitis C, the second one previously treated with interferon. The link between both conditions may be hepatitis C being the trigger of this immune polyneuropathy. Guillain-Barré syndrome should be added to the list of conditions associated with hepatitis C.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Enzyme-Linked Immunosorbent Assay
  • Female
  • Hepacivirus / genetics
  • Hepacivirus / immunology
  • Hepatitis C Antibodies / analysis
  • Hepatitis C, Chronic / complications*
  • Hepatitis C, Chronic / therapy
  • Humans
  • Immunoglobulins, Intravenous / therapeutic use
  • Male
  • Middle Aged
  • Plasmapheresis
  • Polyradiculoneuropathy / complications*
  • Polyradiculoneuropathy / therapy
  • RNA, Viral / analysis


  • Hepatitis C Antibodies
  • Immunoglobulins, Intravenous
  • RNA, Viral