Community respiratory viral infection in adult lung transplant recipients

Chest. 1998 Apr;113(4):944-50. doi: 10.1378/chest.113.4.944.


Study objective: To define the epidemiology, clinical manifestations, and long-term complications of respiratory viral infections in adult lung transplant recipients.

Design: Retrospective review of the records of 122 adult lung transplant recipients over a 5-year period at one institution.

Results: Ten episodes of infection with respiratory syncytial virus, parainfluenza, influenza, or adenovirus were identified. All patients presented with symptoms of respiratory tract infection. Two patients died acutely and four patients subsequently had development of obliterative bronchiolitis (OB).

Conclusions: These data suggest community respiratory viral infections cause significant morbidity and mortality in lung transplant recipients. Further prospective studies are warranted to clarify the relationship between respiratory viral infection and OB and to define the optimal therapy for these viral infections.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Aged
  • Community-Acquired Infections / diagnosis
  • Community-Acquired Infections / epidemiology
  • Community-Acquired Infections / virology
  • Female
  • Humans
  • Lung Transplantation*
  • Male
  • Middle Aged
  • Prevalence
  • Respiratory Tract Infections* / diagnosis
  • Respiratory Tract Infections* / epidemiology
  • Respiratory Tract Infections* / virology
  • Retrospective Studies
  • Seasons
  • Time Factors
  • Treatment Outcome