Histopathologic features of the spontaneous pustular lesions of Behçet's syndrome

Int J Dermatol. 1998 Mar;37(3):194-6. doi: 10.1046/j.1365-4362.1998.00276.x.


Background: Papulopustular lesions are common in Behçet's syndrome (BS). A debate exists as to whether they are different from ordinary acne. This has important clinical and pathophysiologic implications.

Objective: The aim of this study was to evaluate the histopathologic features of papulopustular lesions seen both in BS and acne vulgaris (AV).

Methods: Representative samples were obtained from 17 patients with BS and six patients with AV. The detailed histopathologic features were evaluated by a dermatopathologist blinded to the diagnoses.

Results: Considering the epidermis, follicle epithelium, and dermis separately, no differences could be found between the two groups.

Conclusions: The papulopustular lesions seen in these two disorders cannot be distinguished on the basis of clinical and histopathologic findings.

MeSH terms

  • Acne Vulgaris / pathology*
  • Adolescent
  • Adult
  • Behcet Syndrome / pathology*
  • Diagnosis, Differential
  • Female
  • Humans
  • Male
  • Middle Aged
  • Skin Neoplasms / pathology