Iodide supplementation: 200 micrograms daily or 1,500 micrograms weekly?

Z Ernahrungswiss. 1998 Mar;37(1):18-22. doi: 10.1007/pl00007367.


25 euthyroid volunteers were divided into two groups. Each participant of group A received 200 micrograms iodine in the form of diiodotyrosine per day for a period of eight weeks, i.e. 7 x 200 micrograms iodine/week. Each participant of group B received 1,500 micrograms iodide once a week for a period of eight weeks. In addition to the basal excretion of iodine with the collected urine, the excretion values in group A amounted to 67% of the applied dose in the eighth week. In group B, the excretion values amounted to 65% of the applied dose in the eighth week. Hence, no significant difference between both groups was found.

MeSH terms

  • Adult
  • Dietary Supplements
  • Diiodotyrosine / administration & dosage
  • Dose-Response Relationship, Drug
  • Humans
  • Iodides / administration & dosage*
  • Iodides / metabolism
  • Iodine / urine
  • Middle Aged
  • Time Factors


  • Iodides
  • Diiodotyrosine
  • Iodine