Functional connectivity in single and multislice echoplanar imaging using resting-state fluctuations

Neuroimage. 1998 Feb;7(2):119-32. doi: 10.1006/nimg.1997.0315.


A previous report of correlations in low-frequency resting-state fluctuations between right and left hemisphere motor cortices in rapidly sampled single-slice echoplanar data is confirmed using a whole-body echoplanar MRI scanner at 1.5 T. These correlations are extended to lower sampling rate multislice echoplanar acquisitions and other right/left hemisphere-symmetric functional cortices. The specificity of the correlations in the lower sampling-rate acquisitions is lower due to cardiac and respiratory-cycle effects which are aliased into the pass-band of the low-pass filter. Data are combined for three normal right-handed male subjects. Correlations to left hemisphere motor cortex, visual cortex, and amygdala are measured in long resting-state scans.

Publication types

  • Clinical Trial
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Brain / physiology*
  • Cerebrovascular Circulation / physiology
  • Data Interpretation, Statistical
  • Functional Laterality / physiology
  • Head Movements / physiology
  • Humans
  • Image Interpretation, Computer-Assisted / methods*
  • Magnetic Resonance Imaging / methods*
  • Magnetic Resonance Imaging / statistics & numerical data
  • Male
  • Motor Cortex / physiology
  • Oxygen / blood
  • Parietal Lobe / physiology


  • Oxygen