Premedication for neonatal intubation

Am J Perinatol. 1998 Apr;15(4):213-6. doi: 10.1055/s-2007-993928.

Abstract

The incidence of complications was recorded for 269 consecutive neonatal endotracheal intubations after instituting a routine policy of premedication. Two hundred and fifty-three of the intubations were premedicated with a combination of atropine, fentanyl and succinylcholine, 194 were without incident, 28 required two attempts, 22 required more than two attempts, and 9 required a second attempt with a smaller endotracheal tube. All infants were successfully intubated. We conclude that a policy of routine neonatal premedication for intubation is safe, feasible, and humane.

Publication types

  • Comparative Study

MeSH terms

  • Adjuvants, Anesthesia / administration & dosage
  • Adjuvants, Anesthesia / therapeutic use
  • Anesthetics, Intravenous / administration & dosage
  • Anesthetics, Intravenous / therapeutic use
  • Atropine / administration & dosage
  • Atropine / therapeutic use
  • Birth Weight / physiology
  • Cohort Studies
  • Fentanyl / administration & dosage
  • Fentanyl / therapeutic use
  • Humans
  • Infant
  • Infant, Newborn / physiology*
  • Intermittent Positive-Pressure Ventilation
  • Intubation, Intratracheal / adverse effects
  • Intubation, Intratracheal / methods*
  • Neuromuscular Depolarizing Agents / administration & dosage
  • Neuromuscular Depolarizing Agents / therapeutic use
  • Premedication / adverse effects
  • Premedication / methods*
  • Succinylcholine / administration & dosage
  • Succinylcholine / therapeutic use

Substances

  • Adjuvants, Anesthesia
  • Anesthetics, Intravenous
  • Neuromuscular Depolarizing Agents
  • Atropine
  • Succinylcholine
  • Fentanyl