Analysis and design of three-stranded coiled coils and three-helix bundles

Fold Des. 1998;3(2):R29-40. doi: 10.1016/S1359-0278(98)00011-X.


Three-stranded coiled coils and three-helix bundles are increasingly being identified in proteins. Design and engineering on the scaffolds of these motifs is a potential route towards combating associated viral infections as well as introducing novel functional sites.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Binding Sites
  • Carrier Proteins / chemistry
  • Lectins / chemistry
  • Mannose-Binding Lectins
  • Models, Molecular
  • Protein Conformation*
  • Protein Folding
  • Protein Structure, Secondary*
  • Proteins / chemistry*
  • Viral Envelope Proteins / chemistry


  • Carrier Proteins
  • Lectins
  • Mannose-Binding Lectins
  • Proteins
  • Viral Envelope Proteins