The epidemiology of hyperuricaemia and gout in Taiwan aborigines

Br J Rheumatol. 1998 Mar;37(3):258-62. doi: 10.1093/rheumatology/37.3.258.

Abstract

To determine the prevalence of hyperuricaemia, gout and gout-related factors in Central Taiwan Atayal aborigines, 342 subjects over 18 yr old were interviewed and examined. A questionnaire was designed to screen for signs and symptoms of gout and gout-related risk factors. Serum uric acid, triglyceride and creatinine were measured in all subjects. The prevalence of hyperuricaemia was 41.4% and that of gout 11.7% in aborigines. The uric acid level was 7.9+/-1.7 mg/dl in males and 5.7+/-1.5 in females, and differed significantly under age 70 yr (P < 0.001). Significantly increased triglyceride, creatinine and alcoholism was found in gouty patients compared with non-gouty patients. In 40 cases with gout, 54% had tophi and 35% of their first-degree relatives had gout. The high prevalence of hyperuricaemia and gout in Taiwan Atayal aborigines, a significant family predisposition, increased creatinine level and alcoholism suggest multiple factors affecting the hyperuricaemia.

MeSH terms

  • Adult
  • Age Distribution
  • Aged
  • Asian Continental Ancestry Group
  • Body Mass Index
  • Cholesterol / blood
  • Continental Population Groups
  • Female
  • Gout / blood
  • Gout / ethnology*
  • Humans
  • Male
  • Middle Aged
  • Oceanic Ancestry Group*
  • Prevalence
  • Quality of Health Care
  • Regression Analysis
  • Risk Factors
  • Sex Distribution
  • Taiwan / epidemiology
  • Triglycerides / blood
  • Uric Acid / blood*

Substances

  • Triglycerides
  • Uric Acid
  • Cholesterol