Distribution of dopamine in the rat cerebral cortex

J Neural Transm. 1976;38(3-4):173-80. doi: 10.1007/BF01249437.


The rat cerebral neocortex was sectioned by 3 transverse cuts and analyzed for dopamine and noradrenaline. Dopamine concentration decreased gradually from the rostral (97 +/- 4 ng/g) to the caudal (59 +/- 2 ng/g) end of the neocortex. Also, the noradrenaline concentration was highest in the rostral part (269 +/- 6 ng/g) and decreased gradually reaching a concentration of 238 +/- 3 ng/g in the caudal part. Since the quotient dopamine/noradrenaline showed similar changes in the neocortex parts investigated the data support the view that dopamine serves as a transmitter in cortical neurons apart from being a precursor for noradrenaline.

MeSH terms

  • Animals
  • Cerebral Cortex / analysis*
  • Dopamine / analysis*
  • Male
  • Norepinephrine / analysis
  • Rats


  • Dopamine
  • Norepinephrine